<!DOCTYPE html>
<style>
#target {
display: grid;
grid-auto-flow: column;
grid-template-rows: 100px;
align-items: baseline;
inline-size: min-content;
block-size: 100px;
border: solid 3px;
}
#target > div {
margin: 5px 7px 9px 11px;
}
#target > :nth-child(1) {
background: lime;
font-size: 30px;
}
#target > :nth-child(2) {
background: hotpink;
font-size: 20px;
}
#target > :nth-child(3) {
background: cyan;
writing-mode: vertical-rl;
width: 40px;
height: 40px;
}
</style>
<div id="target">
<div>line1<br>line2</div>
<div>line1<br>line2</div>
<div></div>
</div>